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AB0228 Peripheral fractures and bone density of the lumbar spine in women
  1. NV Toroptsova,
  2. NV Demin,
  3. LI Benevolenskaya
  1. Epidemiology and Genetics, Institute of Rheumatology, Moscow, Russia


Objectives The purpose of the study was to determine the prevalence of osteoporosis in lumbar spine and peripheral fractures after 40 years in women 55 and elder.

Methods Cross-sectional study of 2155 women using bone mineral density (BMD) with DEXA (Hologic 4500 A and W). Retrospective fracture history after 40 years was collected by interview.

Results The prevalence of osteoporosis in lumbar spine according WHO-criteria was 29,8%. Fractures due fall were found in 31% of women. Over 50% of the fractures were of the wrist. There were no significant differences in age, anthropometric properties, number of children, age of menopause and duration of menopause between patients with retrospective fracture (RF) history and without fractures (WF). The prevalence of osteoporosis in lumbar spine in RF vs WF was 32% and 17% respectively. There was significant difference in the BMD of lumbar spine between RF and WF groups (0,828 g/cm2 and 0,874 g/cm2 respectively, p < 0,001).

Conclusion Our study presents the high prevalence of osteoporosis in lumbar spine in postmenopausal women. We found negative association between BMD of lumbar spine and peripheral fractures, so the patients with peripheral fractures are at high risk of osteoporosis, who needs BMD measurements.

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