Background Reflex sympathetic dystrophy (RSD) is a complex syndrome characterised by pain and oedema of one or more extremities, trophic skin changes and vasomotor instability. Long-term outcome is variable and can induce severe consequences. Barbiturates has been related with RSD in 15% of the cases.
Objectives The aim of our work is to define long-term outcome and response to therapy of three patients with RSD following barbiturates use.
Results Main results are expressed in the next Table 1:
Conclusion RSD can be induced with barbiturates therapy. In our experience barbiturates discontinuation is insufficient for improving and response to other therapies can be limited with significant long-term disability.
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