Objectives The evolution of nerve conduction studies and EMG was determined following 30 patients with chronic renal failure maintained on regular haemodialysis for 12 men for 12 months.
Methods Eighteen different electroneurographic (ENG) indices were compared in three groups of patients of different dialysis duration.
Results No relationship was found between neuropathy and duration of haemodialysis. No correlation was found between all ENG indices and the age and sex. Also, nerve conduction was independent of the disease underlying renal failure. The side of arteriovenous vascular access had no statistically significant effect on motor nerve conduction studies in the upper extremities.
ENG indices showed no significant correlation with serum creatinine, PTH, and beta 2 microglobulin.
Mean motor nerve conduction velocity (MNCV) and distal latency (DL) were significantly different (decreased and increased respectively) at the beginning of the study and one year later for the median, ulnar, and common peroneal nerves on both sides. The change was more in patients with low Kt/V (a depuration index) than those with high Kt/V.
Conclusion At the end of the study all patients had had peripheral polyneuropathy, 8 patients (26.7%) had got CTS, and 8 patients (26.7%) had subclinical median mononeuropathy. Axonal neuropathy was present in 100% of patients and demyelinating neuropathy was present in 8 patients (26.7%).