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FRI0252 Eosinophilic myositis associated with behcet’s disease
  1. B Coleiro,
  2. C Mallia
  1. Department of Medicine, St Luke’s Hospital, Pieta, Malta


Behcet’s disease, a systemic vasculitis of unknown aetiology, has a variety of clinical manifestations, the commoner ones including recurrent oro-genital ulceration, uveitis and rashes. Muscular involvement is an uncommon clinical feature and a review of the literature by Worthmann F et al.1 suggests that the myositis passes through two different stages of inflammation: a granulocytic-monocytic phase followed by a predominantly lymphocytic infiltration phase. We present the case of a 24 year old male who satisfies the International Study Group criteria for the diagnosis of Behcet’s disease,2 and who developed features of a localised myositis which differs from that described in the literature in that, histologically, the inflammatory cell infiltrate included significant eosinophilia.


  1. Worthmann F, et al. Muscular involvement in Behcet’s disease: Case report and review of the literature. Neurosci Disord. 1996;6(4):247–53

  2. International Study Group for Behcet’s Disease. Criteria for diagnosis of Behcet’s disease. Lancet 1990;335:1078–80

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