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FRI0252 Eosinophilic myositis associated with behcet’s disease
  1. B Coleiro,
  2. C Mallia
  1. Department of Medicine, St Luke’s Hospital, Pieta, Malta

Abstract

Behcet’s disease, a systemic vasculitis of unknown aetiology, has a variety of clinical manifestations, the commoner ones including recurrent oro-genital ulceration, uveitis and rashes. Muscular involvement is an uncommon clinical feature and a review of the literature by Worthmann F et al.1 suggests that the myositis passes through two different stages of inflammation: a granulocytic-monocytic phase followed by a predominantly lymphocytic infiltration phase. We present the case of a 24 year old male who satisfies the International Study Group criteria for the diagnosis of Behcet’s disease,2 and who developed features of a localised myositis which differs from that described in the literature in that, histologically, the inflammatory cell infiltrate included significant eosinophilia.

References

  1. Worthmann F, et al. Muscular involvement in Behcet’s disease: Case report and review of the literature. Neurosci Disord. 1996;6(4):247–53

  2. International Study Group for Behcet’s Disease. Criteria for diagnosis of Behcet’s disease. Lancet 1990;335:1078–80

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