Background Prevalence of gout in the population of Russian cities 20 years ago according to the data of multicentral study was 0.02–0.06%. Since that time there were no studies on epidemiology of this disease.
Objectives To assess the prevalence and clinical manifestations of gout among Sakhalin population (residents of Yuzhno-Sakhalin city).
Methods Clinical manifestations in 120 gout pts (M:F = 117:3) examined in Municipal Diagnostical Centre of the city of Yuzhno-Sakhalinsk from 1990 to 1999 were studied. Population of the city includes 7% of Koreans and the rest are Slavs.
Results In the result of analysis it was found that gout prevalence among Korean population (300 per 100000 of population) was 6.3 times higher than among Slavs (47 per 100000). In Korean population the disease was found only in males and in Slavs the relation M:F = 26:1. Among Slavs the median period of gout attack was 7–10 days per year whereas in Koreans 3–5 days by 4–5 times a year. Tofies in Koreans were found in 2% of cases, and in the rest – in 17%. Family aggregation of the disease was noticed in 25% of Korean pts and 7% in pts of other ethnicity.
Conclusion In similar environmental circumstances the prevalence and clinical manifestations of gout are closely related to nationality, that is the certain genotype.
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