Objectives The aim of this study was to investigate the influence of the bone mineral density (BMD) and body mass index (BMI) on the knee osteoarthritis (OA).
Methods Seventyfive patients were taken in this study. BMD was measured using dual X-ray absorptiometry (Dexa). Measurements of the spine were made at L1-L4 and of the hip at three sites (femoral neck, Ward’s region and trochanter). The BMI, an indicator of obesity was calculated as the weight divided by the height squared (kg/m2). The knee OA was assessed from a weight-bearing anteroposterior radiograph. Osteophytes and joint space narrowing were evaluated seperately. Individual radiographic features (IRF) rating method was used for grading of osteophytes (0–3) and joint space narrowing (0–3).
Results The mean age of the women was 67 years (48–75) and of the 23 men was 61 years (45–66). There was a highly positive correlation between BMD and OA with BMI(p < 0.01, p < 0.01 respectively). The density of the lumbar spine and the 3 proximal femur sites was significantly larger in men than in women. Mean femoral BMD was correlated with joint space narrowing but not with osteophytosis (p < 0.05). There was no relationship between the density of the lumbar spine with knee OA.
Conclusion There is a clear link between BMD and BMI with the knee OA. These results suggest that mechanical factors are important in the pathophysiology of these diseases.