Objectives Intra-articular injection of HA, a visco-supplement, can be an interesting option to treat OA; it has been mostly studied for OA of the knee. We studied the short-term tolerance and efficacy of an intra-articular injection of Hylane G-F 20 (Synvisc) in hip OA.
Methods We performed an open prospective study in patients with OA of the hip (radiological and/or CT scan criteria: Kellgren radiological score 40 mm and/or Lequesne score >6), without surgery schedule for one year and without any pathology which may contribute to the pain. For each patient, articular amplitudes, VAS and Lequesne score were recorded at day 0,30,60,90,120. The injection of one vial of the drug was realised after radiological verification of the position of the needle by injecting 1/2 cc of a iodic contrast fluid. After
Results 30 injections were performed in 22 patients (13 F + 9 M), mean aged 54.7 years (37–83). The Kellgren score was: stade 1(2); st 2(11); st 3(9). Two patients with iode allergy were pre-treated by hydroxyzine. The patients received analgesics (all); NSAID (11); MOA (15).
Conclusion Hylane G-F20 injection in the hip joint appeared to be well tolerated. It may have a special interest in patients <60 years old suffering from hip OA, notably for delaying surgery.
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