Objectives The aim of this study was to evaluate the functional status and quality of life and to determine the relationship between disability and clinical variables in a group of patients with ankylosing spondylitis (AS).
Methods Fifty-one patients with a mean age of 37.2 years were included to the study. Clinical variables including pain by visual analogue scale (VAS), functional indices by Bath ankylosing spondylitis functional index (BASFI), Dutch functional index (DFI) and Dougdas functional index (FI), metrology by Bath ankylosing spondylitis metrology index (BASMI) and disease activity by Bath ankylosing spondylitis disease activity index (BASDAI) were studied. Radiographs of the patients were scored by Bath ankylosing spondylitis radiological index (BASRI) and quality of life was assessed by Nottingham health profile (NHP). Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels were also recorded.
Results The scores of BASMI and BASRI were correlated with disease duration and BASDAI scores. Functional loss assessed by BASFI, DFI and FI were strongly correlated with BASDAI, BASRI and BASMI. Patients with peripheral joint involvement had greater disability. Functional loss was more correlated with the levels of CRP than ESR. NHP scores best correlated with functional indexes followed by BASDAI.
Conclusion In conclusion, functional loss should be considered in evaluation of AS patients. These functional indexes can help to assess the patients more objectively and monitorize the treatment in order to increase the quality of life in patients suffering from this chronic condition.
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