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AB0127 Thyroid hormones in patients with ankylosing spondilitis or psoriatic arthritis
  1. AT Kotulska1,
  2. EJ Kucharz1,
  3. J Go?dzik1,
  4. D Kapo³ka2,
  5. W Liwoch-Morzo³2
  1. 1Internal Medicine and Rheumatology, Medical University of Silesia, Katowice
  2. 2Division Rheumatology, Silesian Hospital of Rheumatology, Ustroñ, Poland


Background Ankylosing spondylitis (AS) and psoriatic arthritis (PA) are diseases related to a group of arthritides known as seronegative spondyloarthropaties. Exraaarticular manifestations of SA or PS are a common feature. Thyroid gland involvement have been reported in almost all systemic rheumatic disorders.

Objectives The present study was designed to evaluate serum thyroid hormones in patients with SA or PA.

Methods Fourty patients (11F, 29M) aged 52.2 + 1.9 yrs with AS and 13 patients (4F, 9M) aged 46.4 + 11.2 yrs with PA as well as 10 healthy subjects (3F, 7M) aged 51.2 + 2.6 yrs were investigated.

Serum thyroid hormones and thyrotropin levels were measured in all investigated individuals.

Results A decrease in total triiodothyronine and total and free thyroxine was found in the AS patients. No changes in thyroid hormone levels were found in the PS patients.

There was no correlation between the hormone levels, age, ESR and duration of symptoms, except negative correlation between free triiodothyronine and ESR in the controls (r = -0.5977), ESR and total triiodothyronine (r = -0.2160) and ESR and total thyroxine (r = 0.2321) in the AS patients.

Conclusion From clinical point of view, thyroid involvement in AS or PA seems to be less important than in patients with other systemic rheumatic diseases.

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