Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage

P Garnero; M Piperno; E Gineyts; S Christgau; P D Delmas; E Vignon

doi:10.1136/ard.60.6.619

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Extended report

Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage

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Online download statistics by month: May 2001 to March 2024

	Abstract	Full	Pdf
May 2001	125	130	77
Jun 2001	43	207	131
Jul 2001	23	109	38
Aug 2001	5	63	31
Sep 2001	12	50	16
Oct 2001	11	33	18
Nov 2001	5	46	12
Dec 2001	8	24	16
Jan 2002	8	37	9
Feb 2002	7	29	9
Mar 2002	1	22	11
Apr 2002	6	40	18
May 2002	5	23	8
Jun 2002	5	27	8
Jul 2002	7	27	9
Aug 2002	3	15	11
Sep 2002	2	28	15
Oct 2002	10	40	14
Nov 2002	6	14	16
Dec 2002	4	21	13
Jan 2003	3	20	9
Feb 2003	3	23	15
Mar 2003	4	35	23
Apr 2003	4	20	15
May 2003	4	19	12
Jun 2003	5	16	14
Jul 2003	16	46	10
Aug 2003	28	25	8
Sep 2003	31	48	35
Oct 2003	36	72	26
Nov 2003	50	63	23
Dec 2003	27	42	12
Jan 2004	39	77	23
Feb 2004	21	29	15
Mar 2004	40	37	15
Apr 2004	24	53	34
May 2004	48	67	13
Jun 2004	55	73	26
Jul 2004	43	74	25
Aug 2004	44	67	30
Sep 2004	29	93	49
Oct 2004	31	110	37
Nov 2004	31	102	79
Dec 2004	14	70	38
Jan 2005	13	143	63
Feb 2005	25	110	44
Mar 2005	28	92	75
Apr 2005	10	71	57
May 2005	17	39	48
Jun 2005	14	52	40
Jul 2005	13	66	51
Aug 2005	12	43	42
Sep 2005	7	74	43
Oct 2005	14	81	48
Nov 2005	15	94	73
Dec 2005	11	66	41
Jan 2006	9	93	31
Feb 2006	10	101	34
Mar 2006	10	96	57
Apr 2006	13	67	39
May 2006	30	45	35
Jun 2006	20	25	23
Jul 2006	19	50	28
Aug 2006	16	45	36
Sep 2006	19	42	26
Oct 2006	41	74	53
Nov 2006	31	48	34
Dec 2006	28	40	30
Jan 2007	46	65	66
Feb 2007	25	38	35
Mar 2007	49	43	30
Apr 2007	38	18	12
May 2007	27	14	18
Jun 2007	30	15	16
Jul 2007	34	17	21
Aug 2007	26	15	15
Sep 2007	34	16	12
Oct 2007	38	22	19
Nov 2007	27	16	16
Dec 2007	24	8	10
Jan 2008	19	13	15
Feb 2008	43	7	13
Mar 2008	43	9	22
Apr 2008	23	12	12
May 2008	32	4	7
Jun 2008	26	7	11
Jul 2008	43	3	3
Aug 2008	47	5	5
Sep 2008	47	0	7
Oct 2008	35	1	7
Nov 2008	47	1	8
Dec 2008	23	2	5
Jan 2009	23	7	9
Feb 2009	38	6	5
Mar 2009	37	6	10
Apr 2009	22	5	10
May 2009	25	7	9
Jun 2009	27	6	9
Jul 2009	35	11	13
Aug 2009	26	3	3
Sep 2009	29	9	2
Oct 2009	37	4	5
Nov 2009	36	5	11
Dec 2009	28	4	13
Jan 2010	26	4	6
Feb 2010	20	7	9
Mar 2010	25	16	13
Apr 2010	33	12	9
May 2010	13	12	11
Jun 2010	15	3	6
Jul 2010	13	0	3
Aug 2010	14	5	8
Sep 2010	11	5	5
Oct 2010	27	6	10
Nov 2010	20	8	7
Dec 2010	20	7	7
Jan 2011	27	2	2
Feb 2011	19	6	10
Mar 2011	25	4	6
Apr 2011	29	1	1
May 2011	21	4	4
Jun 2011	15	6	6
Jul 2011	32	5	9
Aug 2011	24	4	4
Sep 2011	40	5	5
Oct 2011	50	13	10
Nov 2011	36	12	10
Dec 2011	38	15	9
Jan 2012	18	14	13
Feb 2012	60	18	17
Mar 2012	39	7	14
Apr 2012	36	14	18
May 2012	58	25	22
Jun 2012	36	16	17
Jul 2012	42	24	17
Aug 2012	36	18	23
Sep 2012	57	16	20
Oct 2012	55	25	16
Nov 2012	51	26	17
Dec 2012	38	20	15
Jan 2013	49	30	10
Feb 2013	62	13	22
Mar 2013	40	21	14
Apr 2013	45	24	18
May 2013	51	16	28
Jun 2013	21	16	18
Jul 2013	23	12	19
Aug 2013	26	11	11
Sep 2013	39	15	16
Oct 2013	44	7	14
Nov 2013	45	16	26
Dec 2013	35	18	33
Jan 2014	35	12	22
Feb 2014	26	19	17
Mar 2014	44	14	21
Apr 2014	44	13	19
May 2014	63	20	8
Jun 2014	41	27	19
Jul 2014	52	9	16
Aug 2014	34	11	7
Sep 2014	39	20	13
Oct 2014	58	27	26
Nov 2014	45	19	17
Dec 2014	31	16	11
Jan 2015	43	9	6
Feb 2015	42	10	15
Mar 2015	54	11	21
Apr 2015	18	5	9
May 2015	36	12	16
Jun 2015	24	16	3
Jul 2015	36	15	16
Aug 2015	25	9	3
Sep 2015	57	10	11
Oct 2015	19	3	5
Nov 2015	36	6	19
Dec 2015	39	4	4
Jan 2016	51	17	12
Feb 2016	56	12	11
Mar 2016	30	11	18
Apr 2016	40	4	10
May 2016	41	10	15
Jun 2016	16	7	13
Jul 2016	22	10	15
Aug 2016	28	9	10
Sep 2016	30	5	11
Oct 2016	82	13	17
Nov 2016	46	11	20
Dec 2016	32	10	7
Jan 2017	29	12	5
Feb 2017	22	9	10
Mar 2017	20	8	10
Apr 2017	14	18	16
May 2017	15	26	7
Jun 2017	14	19	8
Jul 2017	36	19	6
Aug 2017	50	30	5
Sep 2017	55	27	10
Oct 2017	85	39	11
Nov 2017	91	29	18
Dec 2017	350	318	9
Jan 2018	98	66	9
Feb 2018	266	216	6
Mar 2018	90	56	7
Apr 2018	151	118	15
May 2018	135	105	8
Jun 2018	73	51	13
Jul 2018	86	42	8
Aug 2018	100	94	10
Sep 2018	73	47	6
Oct 2018	165	131	13
Nov 2018	166	116	14
Dec 2018	132	113	8
Jan 2019	102	72	13
Feb 2019	74	56	16
Mar 2019	55	34	11
Apr 2019	27	13	15
May 2019	21	17	8
Jun 2019	34	14	14
Jul 2019	28	23	9
Aug 2019	31	17	9
Sep 2019	19	13	13
Oct 2019	30	14	7
Nov 2019	60	47	14
Dec 2019	14	12	12
Jan 2020	24	16	13
Feb 2020	25	13	12
Mar 2020	24	21	9
Apr 2020	35	23	20
May 2020	53	45	10
Jun 2020	19	13	13
Jul 2020	31	17	5
Aug 2020	20	12	8
Sep 2020	36	20	21
Oct 2020	26	18	14
Nov 2020	36	20	15
Dec 2020	35	25	32
Jan 2021	40	26	16
Feb 2021	29	18	9
Mar 2021	41	23	14
Apr 2021	31	17	15
May 2021	26	19	14
Jun 2021	27	27	21
Jul 2021	22	22	17
Aug 2021	13	13	9
Sep 2021	45	45	42
Oct 2021	46	38	25
Nov 2021	42	28	38
Dec 2021	32	18	15
Jan 2022	23	19	6
Feb 2022	49	46	28
Mar 2022	45	36	18
Apr 2022	37	29	18
May 2022	52	44	36
Jun 2022	49	39	9
Jul 2022	42	34	20
Aug 2022	46	34	5
Sep 2022	52	47	16
Oct 2022	46	36	11
Nov 2022	50	38	12
Dec 2022	23	20	11
Jan 2023	72	50	15
Feb 2023	82	57	13
Mar 2023	47	35	4
Apr 2023	28	22	8
May 2023	33	20	16
Jun 2023	37	24	15
Jul 2023	35	11	16
Aug 2023	31	21	12
Sep 2023	34	16	6
Oct 2023	79	61	37
Nov 2023	41	27	10
Dec 2023	127	24	6
Jan 2024	92	2	2
Feb 2024	46	5	4
Mar 2024	171	6	0
Total	10592	8748	4826

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