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Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) as recurrence of aborted PMR
  1. M A CIMMINO
  1. E SILVESTRI,
  2. G GARLASCHI
  1. Clinica Reumatologica, DIMI
  2. Università di Genova, Italy
  3. Sezione di Diagnostica per Immagini, DIMES
  4. Università di Genova, Italy

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A comparison of clinical and laboratory findings in patients with RS3PE alone, PMR alone, and RS3PE associated with PMR has been recently published by Cantini et al.1 Their results suggest that the three conditions might represent a continuum, with PMR, a more severe condition, at one end and, RS3PE alone, at the other. PMR has a longer duration, is more commonly associated with systemic symptoms, requires higher doses of steroids for a longer time, and shows more relapses and recurrences. Although Cantini et alemphasised the similarities between PMR and RS3PE, they concluded that RS3PE alone is a separate entity. Other studies by the same group of authors have shown that RS3PE may be a feature of different diseases, such as spondyloarthropathies, psoriatic arthritis, rheumatoid arthritis (RA), acute sarcoidosis, and neoplasms.2 Whether RS3PE is a distinct syndrome or a clinical …

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