The European classification criteria (ECC) include salivary scintigraphy (SSC) for diagnosing Sjögren's syndrome (SS).1 The performance of this test has been established without considering the ECC for either confirming or excluding SS.1-6 This pilot study aimed at evaluating the performance of the qualitative reading of SSC, performing a clinical measurement of SSC, and establishing the most discriminatory scintigraphic parameters for diagnosing SS in a Spanish population fulfilling the ECC.

This cross sectional study included consecutive patients referred for SCC: 15 healthy volunteers (eight women, seven men; mean (SD) age 50.6 (17.5)), 16 patients with SS based on the ECC (15 women, one man; age 58.1 (10.4)), and 15 xerostomic patients who did not fulfil the ECC, as controls (seven women, eight men; age 53.3 (19.0); AIDS (n=3), chronic parotitis (n=2), sarcoidosis (n=2), or taking drugs that cause dryness (n=8)).

Patients underwent a sufficient number of tests included in the ECC set, if not all, …