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Anti-dsDNA antibodies associated with acute EBV infection in Sjögren's syndrome
  1. E Y PADALKO,
  2. X BOSSUYT
  1. Laboratory Medicine, Immunology
  2. University Hospitals Leuven
  3. Herestraat 49
  4. 3000 Leuven, Belgium
  1. Dr Bossuyt

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The role of viral infection in the pathogenesis of autoimmune diseases is not clear. Some authors have suggested a role for herpes viruses and retroviruses in the pathogenesis of systemic rheumatic diseases,1-4 whereas others have produced evidence against this idea.5-7 In this report we present a case in which an association was found between Epstein-Barr virus (EBV) infection and anti-DNA antibodies in a patient with Sjögren's syndrome.

A 28 year old woman was diagnosed with Sjögren's syndrome. The clinical presentation …

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Footnotes

  • This work was presented at the 52nd AACC annual meeting, San Francisco, CA in June 2000 and has been published in abstract form in Clin Chem 2000;46(suppl 6):A44.