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HLA-DRB1*04 may be a marker of severity in giant cell arteritis
  1. MIGUEL A GONZALEZ-GAY,
  2. CARLOS GARCIA-PORRUA
  1. ALI H HAJEER,
  2. ADELE DABABNEH,
  3. WILLIAM E R OLLIER
  1. Rheumatology Division
  2. Hospital Xeral-Calde
  3. Lugo, Spain
  4. ARC Epidemiology Unit
  5. Manchester University Medical School
  6. Manchester, UK
  1. Dr Miguel A Gonzalez-Gay, Section of Rheumatology, Hospital Xeral-Calde Lugo, c/ Dr Ochoa s/n, 27004 Lugo, Spain.

https://doi.org/10.1136/ard.59.7.574a

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    Salvarani et al recently studied 39 patients with giant cell arteritis (GCA) and found no association with HLA-DRB1*04.1 In contrast, previous immunogenetic studies did show an association between HLA-DRB1*04 and GCA.2 ,3Rauzy et al, also, reported a significant increase in DRB1*04 frequency in GCA. HLA-DRB1*04 was present in 20 of their 41 patients …

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