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I read with interest the article recently published by Punziet al.1 The results shown in this study demonstrate higher levels of acute phase reaction markers such as ESR and CRP in elderly onset psoriatic arthritis patients (EOPsA) than those displayed by young onset psoriatic arthritis patients (YOPsA). The authors included 16 EOPsA (>60 years) and 50 YOPsA (<60 years).
I would like to comment that the information regarding normal values was restricted to the following words “CRP, normal values <0.6 mg/dl”, no other information is given. It is not possible to know how and from whom these normal values were obtained. Even if a commercial test that includes their own controls was used, it is clear that you will need to test groups of normal subjects that cover the age spectrum of both …
Dr L Punzi, Cattedra e Divisione di Reumatologia, Policlinico Università, via Giustiniani 2, 35128 Padova, Italy