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Correspondence
HLA-B27+ anterior uveitis with or without associated spondyloarthritis: clinical and immunological features
  1. FRANCISCO RIVERA-CÍVICO,
  2. JUAN JIMÉNEZ-ALONSO,
  3. MARÍA MARTÍN-ARMADA,
  4. MARÍA TERESA HERRANZ,
  5. JOSÉ CASTRO,
  6. FRANCISCO PÉREZ-ALVAREZ,
  7. J L DEL ARBOL
  1. MANUEL TORIBIO
  1. FRANCISCO SAMANIEGO
  1. Service of Internal Medicine
  2. Service of Ophthalmology
  3. Service of Clinical Chemistry and Immunology, “Virgen de las Nieves” University Hospital, Granada, Spain
  1. Dr J Jiménez-Alonso, Jefe del Servicio de Medicina Interna, Hospital General de Especialidades “Virgen de las Nieves” Avda Fuerzas Armadas 2, 18014 Granada, Spain.

https://doi.org/10.1136/ard.58.11.721

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    Anterior uveitis (AU) is the most common form of uveitis,1-3 and may be produced by different causes. An aetiological diagnosis is commonly established in approximately half of the patients with AU, being seronegative spondyloarthropathies (SA), and mainly ankylosing spondylitis, the most frequent cause of the disease. Approximately 50% of the patients with AU are HLA-B27 positive; half of them usually presenting with associated SA,4-8 the other half are patients with HLA-B27+ but with no associated articular disease (HLA-B27+ AU). Several clinical features have been described to be common in patients with AU associated with HLA-B27, however, these features are similar either in patients with or without associated SA.9 ,10 This is why we conducted this clinical and immunological study in patients with AU positive for HLA-B27 with the aim of discovering the differences between …

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