Table 5
Serial measurements of urinary, immunological, and renal haemodynamic parameters of two groups according to the improvement of GFR
| Group 1 (n=14) | Group 2 (n=17) | ||||||
|---|---|---|---|---|---|---|---|
| Pretreatment | Post-treatment | p Value | Pretreatment | Post-treatment | p Value | ||
| Proteinuria (g/24h) | 4.0 (2.4) | 1.3 (1.0) | <0.01 | 4.5 (2.9) | 1.6 (1.4) | <0.01 | |
| Anti-DNA (U/ml)* | 235 (318) | 10 (8) | <0.01 | 202 (307) | 7 (5) | <0.01 | |
| CH50 (U/ml) | 15.5 (5.9) | 37.8 (7.5) | <0.01 | 15.8 (8.3) | 37.6 (11.2) | <0.01 | |
| GFR (ml/min) | 57.3 (22.0) | 61.4 (20.2) | NS | 54.5 (29.1) | 99.6 (30.9) | <0.01 | |
| RPF (ml/min) | 588.5 (223.9) | 400.8 (141.3) | <0.01 | 549.7 (216.6) | 560.7 (170.6) | NS | |
| FF (%) | 10.0 (2.9) | 15.6 (2.8) | <0.01 | 10.7 (5.7) | 18.2 (4.4) | <0.01 | |
-
Values are mean (SD). Anti-DNA=anti-DNA antibody; CH50=total haemolytic complement activity. Other abbreviations as table 2.*Anti-DNA antibody was analysed in 13 patients in group 1, and 15 patients in group 2.
