Article Text

PDF

Hydroxychloroquine and lupus pregnancy: review of a series of 36 cases.
  1. N M Buchanan,
  2. E Toubi,
  3. M A Khamashta,
  4. F Lima,
  5. S Kerslake,
  6. G R Hughes
  1. Lupus Pregnancy Clinic, St Thomas' Hospital, London, United Kingdom.

    Abstract

    OBJECTIVE: To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ). METHODS: The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus activity, obstetric experience, and infant outcome. RESULTS: HCQ was not apparently teratogenic. Lupus activity and obstetric outcome in the two groups were similar. CONCLUSION: HCQ continuation is probably safe during pregnancy in patients with lupus, but there is no obvious advantage in commencing treatment.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.