Article Text


Rapid development of a tophus following ipsilateral hemiparesis.
  1. C F Donegan,
  2. P Berman,
  3. M Doherty
  1. Department of Health Care of the Elderly, City Hospital, Nottingham, United Kingdom.


    An 85 year old man with a longstanding history of non-tophaceous gout developed a single large tophus, unassociated with inflammation, on his paretic leg over a six week period following an acute hemiplegia. The rapidity of tophus formation, its localisation to the paretic limb, and the apparent blunting of the acute inflammatory response represent a previously unreported interaction between gout and neurological deficit.

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