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Remission of scleroderma during chemotherapy for lymphoma.
  1. M Comer,
  2. A R Harvey
  1. Department of Medicine, and Rheumatology, Arrowe Park Hospital, United Kingdom.

    Abstract

    Temporary remission of scleroderma during the successful treatment of an associated malignant lymphoma by chemotherapy is reported in a patient with systemic sclerosis and mixed connective tissue disease. There is a well established relation between malignant disease and polymyositis/dermatomyositis but no overall association with systemic sclerosis or mixed connective tissue disease. Reports of the coexistence of malignancy and systemic sclerosis, however, emphasise a close temporal relation in their occurrence. A review of published work has identified several postulated mechanisms for this relation which may explain the response to chemotherapy.

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