Article Text


Organic brain syndrome with psychosis as an initial manifestation of systemic lupus erythematosus in an elderly woman.
  1. M E Mavrikakis,
  2. L G Antoniades,
  3. J B Germanides,
  4. D Sotou,
  5. A Rassidakis
  1. Department of Clinical Therapeutics, Alexandra Hospital, Athens Medical School, Greece.


    This paper describes a rare case of organic brain syndrome with psychosis and clinically transverse myelopathy, as initial manifestations of systemic lupus erythematosus in an elderly woman. The identification and evaluation of antibodies to ribosome P in the serum and cerebrospinal fluid may be of help in such cases for differential diagnosis. The patient was treated successfully with 30 mg prednisone daily.

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