Article Text

PDF

Nocardia asteroides pneumonia complicating low dose methotrexate treatment of refractory rheumatoid arthritis.
  1. J J Cornelissen,
  2. L J Bakker,
  3. M J Van der Veen,
  4. M Rozenberg-Arska,
  5. J W Bijlsma
  1. Department of Rheumatology, University Hospital Utrecht.

    Abstract

    Low dose methotrexate is used increasingly often in the treatment of rheumatoid arthritis. Severe complications due to toxicity of the lung or bone marrow occur infrequently. This report describes a 71 year old woman with longstanding rheumatoid arthritis who developed pleuritis, a pulmonary infiltrate, and pancytopenia during treatment with low dose methotrexate. Fatal respiratory insufficiency followed, and cultures from the lung after death showed Nocardia asteroides.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.