Ann Rheum Dis 49:641-642 doi:10.1136/ard.49.8.641
  • Research Article

Bone pain as the presenting manifestation of secondary syphilis.

  1. S Middleton,
  2. C Rowntree,
  3. S Rudge
  1. Department of Rheumatology, London Hospital.


      A 31 year old fireman presented with acute pain and tenderness in both shins and forearms. Radiographs were normal but bone scintigraphy showed widespread increased isotope uptake. Serology was consistent with a diagnosis of secondary syphilis, and the patient's symptoms resolved completely six weeks after a course of penicillin.