Article Text

PDF

A prospective study on antiribosomal P proteins in two cases of familial lupus and recurrent psychosis.
  1. R H Derksen,
  2. A P van Dam,
  3. F H Gmelig Meyling,
  4. J W Bijlsma,
  5. R J Smeenk
  1. Division of Immunopathology, Department of Internal Medicine, University Hospital Utrecht, The Netherlands.

    Abstract

    In two siblings with systemic lupus erythematosus (SLE), who experienced two episodes of psychosis each, a longitudinal study of autoantibodies, including antibodies to ribosomal P proteins, is described. In two of three evaluable periods of 15 weeks antedating psychosis a rise followed by a spontaneous drop in anti-P levels was recorded. In the third period antibodies to ribosomal protein P were absent. It is concluded that results with single samples are not informative, and that frequent measurement of antibodies to ribosomal protein P in patients with SLE may have limited predictive value for psychosis.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.