Article Text

PDF

Use of cultured epithelial cells, including keratinocytes, for the detection of antinuclear antibodies.
  1. I Leigh,
  2. F Wojnarowska,
  3. S Burge,
  4. B Bhogal,
  5. T Zhu
  1. Department of Dermatology, London Hospital.

    Abstract

    The use of cultured human epithelial cells as a substrate for the detection of antinuclear antibodies (ANAs) improves the sensitivity of detection above the standard substrates used. Standard antisera have been screened against a series of epithelial cell lines, including keratinocytes. Selected cells have then been used to detect ANAs in 78 patients with discoid lupus erythematosus.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.