Article Text


Plasma exchange in systemic lupus erythematosus.
  1. H F Parry,
  2. C J Moran,
  3. M L Snaith,
  4. J D Richards,
  5. A H Goldstone,
  6. L J Nineham,
  7. F C Hay,
  8. W J Morrow,
  9. I M Roitt


    Eight out of 10 patients studied longitudinally received benefit from plasmapheresis. The patients were used as their own controls, being treated in a steady state as far as was possible. Levels of circulating complexes did not bear a close relationship with clinical results. On the evidence plasma exchange alone does not appear to represent an important part of the long-term management of patients with systemic lupus erythematosus but may well be of value in combination with other therapy.

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