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Effect of D(-)penicillamine on chronic experimental arthritis in rabbits.
  1. I M Hunneyball,
  2. G A Stewart,
  3. D R Stanworth

    Abstract

    Preliminary observations on the effect of D(-)penicillamine on chronic antigen-induced experimental arthritis in rabbits are reported. Daily oral administration of penicillamine, at a dose equivalent to that usually administered to rheumatoid arthritis patients, diminished the arthritis in 2 out of 3 animals as assessed by both measurement of joint circumference and histological examination.

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