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  • Surgery in patients receiving anti-tumour necrosis factor α treatment in rheumatoid arthritis: an observational study on 50 surgical procedures

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Surgery in patients receiving anti-tumour necrosis factor α treatment in rheumatoid arthritis: an observational study on 50 surgical procedures
  1. D Wendling,
  2. J-C Balblanc,
  3. A Brousse,
  4. A Lohse,
  5. G Lehuede,
  6. P Garbuio,
  7. E Toussirot,
  8. B Auge,
  9. D Jacques
  1. Regional Rheumatologic Network for Biotherapies, Department of Rheumatology, University Teaching Hospital, F-25030 Besançon, France
  1. Correspondence to:
    Professor D Wendling
    daniel.wendlingufc-chu.univ-fcomte.fr

https://doi.org/10.1136/ard.2005.037762

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    Currently, little information is available about the interaction between anti-tumour necrosis factor (TNF) treatment and surgery.1

    In an attempt to evaluate the relative safety of anti-TNF and its impact on the course of disease in patients with rheumatoid arthritis (RA) undergoing surgery, we included in a retrospective study all such patients followed up in a regional network. The network allows close follow up as the patients regularly renew their prescription at the hospital. Surgical outcomes focused on infection and other complications together with the postoperative impact on RA disease activity. A flare of RA was defined as an increase in the joint count and global assessment of >20%.

    Fifty surgical procedures were recorded …

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