© 2003 by BMJ Publishing Group & European League Against Rheumatism
LETTER
Bilateral subdural effusion in a patient with neuro-Behçets disease
1 Departments of Immunology and Medicine, St Marianna University School of Medicine
2 Department of Ophthalmology, Uveitis Clinic, Tokyo Womens Medical College, Daini Hospital
Correspondence to:
Correspondence to:
Dr N Suzuki, Departments of Immunology and Medicine, St Marianna University School of Medicine, 2-16-1, Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8511, Japan;
n3suzuki@marianna-u.ac.jp
Accepted 12 August 2002
Keywords: Behçets disease; central nervous system; subdural effusion
| The first 150 words of the full text of this article appear below. |
The central nervous system is sometimes affected in patients with Behçets disease.1 Meningoencephalitis and brainstem lesions are the most common problems. The appearance of subdural effusion has been rarely reported. Our patient, who had neuro-Behçets disease with massive bilateral subdural effusion, was successfully treated with steroid pulse therapy.
The patient (a 45 year old man) first developed polyarthralgia, fever, recurrent oral aphthosis, and headache in 1986. In 1987 he had a genital ulcer and positive pathergy test. Thus, he fulfilled the international criteria for the diagnosis of Behçets disease. He had two cycles of steroid pulse therapy, and his symptoms including headache subsided. In 1995 an episodic exacerbation of the neuro-Behçets disease occurred, accompanying parkinsonism and abnormal cerebral spinal fluid (CSF) findings (cell 5/3, protein 0.97 g/l, IgG 0.07 g/l). The symptoms improved after treatment with prednisolone 40 mg/day + colchicine 1 mg/day.
In December 2000 he began to have
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