Correspondence
A case of Churg-Strauss vasculitis after hepatitis B vaccination
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Vaccination against hepatitis B with recombinant vaccine is highly effective in producing immunity in immunocompetent patients. It has few side effects, usually consisting of early local reactions to the thimerosal or aluminium components of the vaccine. Vasculitis have been reported after BCG inoculation and vaccination against flu, measles, and hepatitis B. For the latter, some cases have been described after inoculation of both plasma derived and recombinant vaccine: cryoglobulinaemia, pulmonary and cutaneous vasculitis, erythema nodosum, Takayasu's arteritis, and polyarteritis nodosa.1-9 We describe a case of Churg-Strauss vasculitis (CSv) developing after vaccination against hepatitis B with recombinant vaccine.
The patient's personal and family histories were negative for
autoimmune and allergic diseases; in particular, neither atopy nor
eczema were reported. The patient's available previous full blood
counts with differential counts were normal. At the age of 20, from
November 1989 to May 1990, using the recommended dosing and time
schedule, she had been vaccinated against HBV
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This article has been cited by other articles:
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SCOTT, D. G I, WATTS, R. A
(2000). Systemic vasculitis: epidemiology, classification and environmental factors. Ann Rheum Dis
59: 161-163
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