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Annals of the Rheumatic Diseases 2009;68:1517-1519; doi:10.1136/ard.2009.112508
Copyright © 2009 BMJ Publishing Group Ltd & European League Against Rheumatism.

EDITORIAL

A magic bullet for gout?

Alexander So, Nathalie Busso

Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Correspondence to:
Correspondence to Professor A So, Department of Rheumatology, University Hospital Lausanne, 1011, Lausanne, Switzerland; alexanderkai-lik.so@chuv.ch

Accepted 22 July 2009

The first 150 words of the full text of this article appear below.

Do we need new treatments for gout? Hyperuricaemia, the metabolic condition underlying gouty inflammation, has attracted recent attention as new urate-lowering treatments emerge on the horizon. For an acute attack of gout, the currently available drugs—non-steroidal anti-inflammatory drugs, colchicine and corticosteroids, seem to do a pretty good job for the majority of patients in relieving the acute symptoms of inflammation. However, recent data have highlighted the epidemiological shifts in the gouty population towards a more elderly group of patients who often present multiple medical problems. This as well as clinical practice have made us aware that our current treatments of acute gout are not ideal in all situations. They may cause significant side effects in patients with poor renal and cardiac function, and practical experience indicates that quite a number of patients with chronic gout end up receiving long-term steroids, with all the side effects that such treatment engenders. Furthermore, . . . [Full text of this article]


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