Life-table analysis of etanercept with or without methotrexate in patients with psoriatic arthritis
Dipartimento di Clinica e Terapia Medica, Rheumatology Unit, Università di Roma, Rome, Italy
Correspondence to:
Professor Antonio Spadaro, Dipartimento di Clinica e Terapia Medica, Rheumatology Unit, Sapienza, Università di Roma, Azienda Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy; a.spadaro.reuma@virgilio.it
Accepted 7 February 2008
| The first 150 words of the full text of this article appear below. |
The recent analysis of data included in the Stockholm TNF
Follow- Up (STURE) registry showed that the concomitant use of methotrexate (MTX) with etanercept (ETN), adalimumab or infliximab was associated with long-term drug survival of anti-tumour necrosis factor (TNF) agents in patients with psoriatic arthritis (PsA).1 The positive effect of MTX was primarily linked to fewer drop-outs due to adverse events.1 This analysis did not consider each anti-TNF drug subgroup. For this reason we determined the cumulative probability of taking ETN with or without MTX in a large cohort of patients.
We prospectively studied 82 patients, admitted to our rheumatological unit since 2001, affected by PsA, classified according to Moll and Wright criteria, modified by Helliwell et al,2 treated with ETN alone or in combination with MTX. The main clinical demographic features of each patient were recorded, including the pattern of articular involvement. Clinical assessment was performed according to
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This article has been cited by other articles:
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SPADARO, A., SCRIVO, R., SPINELLI, F. R., VALESINI, G.
(2009). Monitoring Biological Therapies in Psoriatic Arthritis. The Journal of Rheumatology Supplement
83: 69-70
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