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Annals of the Rheumatic Diseases 2004;63:471-472; doi:10.1136/ard.2003.014589
Copyright © 2004 BMJ Publishing Group Ltd & European League Against Rheumatism.
Annals of the Rheumatic Diseases 2004;63:471-472
© 2004 by BMJ Publishing Group Ltd & European League Against Rheumatism

LEADER

Spondyloarthropathy

How to diagnose axial spondyloarthropathy early

N Barkham, H Marzo-Ortega, D McGonagle, P Emery

Academic Unit of Musculoskeletal Disease, University of Leeds, UK

Correspondence to:
Correspondence to:
Professor P Emery
Academic Unit of Musculoskeletal Disease, 1st Floor, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK; p.emery{at}leeds.ac.uk


A proposed algorithmic approach may be useful in the early detection of AS

Keywords: ankylosing spondylitis; spondyloarthropathy; early diagnosis; back pain; prediction

The first 150 words of the full text of this article appear below.

Physicians’ perceptions of the spondyloarthropathies are changing. Ankylosing spondylitis (AS), the prototype of this group, has traditionally been considered a rare disease with few therapeutic options. In addition, diagnosis is difficult, sometimes delayed for decades, mainly owing to the lack of sensitivity of the traditional imaging method, radiography, to detect the hallmark of AS, sacroiliitis. Also, the widespread perception of these diseases as "innocuous" or having a good outcome has hampered the development of protocols for defining early disease and identifying those patients who would benefit from early treatment.

PROBLEMS OF AS

It is now clear that these assumptions are incorrect. Ankylosing spondylitis is more common than previously estimated, with some studies suggesting a prevalence as high as 1%.1 Importantly it affects people at a time when they are economically active (most commonly in the third decade), and the disease has a major impact on a person’s ability to work. Recent evidence . . . [Full text of this article]


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