© 2002 by Annals of the Rheumatic Diseases
REPORT
Epidemiology, diagnostic possibilities, and treatment of tuberculosis
Robert Koch-Institute, Nordufer 20, 13353 Berlin, Germany
Correspondence to:
Correspondence to:
Dr R Kurth;
KurthR@rki.de
Keywords: epidemiology; diagnosis; treatment; tuberculosis
| The first 150 words of the full text of this article appear below. |
On a worldwide scale, infectious diseases still account for about 25% of all deaths, only surpassed by cardiovascular diseases.1 The picture, however, is dissimilar when industrialised and developing countries are compared. In Germany, for example, only 1% of all deaths are due to infectious diseases, whereas in developing countries—for example, in sub-Saharan Africa 49% of all deaths are due to infections. Mycobacterium tuberculosis is the second biggest killer world wide, with only HIV/AIDS responsible for more deaths. Tuberculosis notification rates in the year 2000 in many developing countries reached 100 or more per 100 000 population.2 A relatively high rate of underreporting has to be assumed for many countries, and estimates reach as high as more than 500 new infections per 100 000 people. In general, tuberculosis is a disease of the poor: the less developed health systems are, the higher the rates of new cases of tuberculosis (fig 1
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