Leader
Stem cell transplantation: limits and hopes
| The first 150 words of the full text of this article appear below. |
 |
Article |
|---|
The clinical course and severity of inflammatory rheumatic diseases vary considerably. A large proportion of patients have mild to moderate activity of the inflammatory process which can be successfully controlled by conventional therapeutic measures: traditional disease modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis (RA) and some other forms of chronic arthritides, intermediate steroid doses or mild immunomodulatory agents for systemic lupus erythematosus (SLE) and other connective tissue diseases. Also, control of more severe disease is often manageable by more aggressive, established means, such as high dose methotrexate and combination treatment for RA, or pulse cyclophosphamide treatment and steroids in SLE. For most of these therapeutic approaches significant evidence has accumulated in randomised controlled trials.1-3
Without the possibility of making individual predictions, there are
many patients whose diseases are not sufficiently responsive to the
traditional measures. At least for RA, the armamentarium has recently
been significantly enriched by new means of
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Article
- Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease
- M Binks, J R Passweg, D Furst, P McSweeney, K Sullivan, C Besenthal, J Finke, H H Peter, J van Laar, F C Breedveld, W E Fibbe, D Farge, E Gluckman, F Locatelli, A Martini, F van den Hoogen, L van de Putte, A V N Schattenberg, R Arnold, P A Bacon, P Emery, I Espigado, B Hertenstein, F Hiepe, A Kashyap, I Kötter, A Marmont, A Martinez, M J Pascual, A Gratwohl, H G Prentice, C Black, and A Tyndall
Ann Rheum Dis 2001 60: 577-584.[Abstract] [Full Text] [PDF]
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
-
Immunology (including allergy)
-
Connective tissue disease
-
Degenerative joint disease
-
Musculoskeletal syndromes
-
Rheumatoid arthritis
- Relevant Article
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
