Preface
Advances in targeted therapies II
| The first 150 words of the full text of this article appear below. |
The papers compiled in this supplement of the
Annals of the Rheumatic Diseases constitute
summaries of presentations at the second International Symposium on
"Advances in Targeted Therapies", which was held in March/April
2000. As such they represent the state of the art on the biology,
mechanisms of action and pathophysiology of tumour necrosis factor 
(TNF) as well as the current knowledge on means and consequences of
blocking this important cytokine.
We are grateful to Drs Crofford, Furst, Feldmann, Klareskog, Lipsky,
Maini, Moreland and Weinblatt, the members of the Advisory Board of the
Symposium, for their invaluable help towards the success of the
conference, the second of a series of similar events planned for the
future. We particularly wish to thank all speakers for their excellent
presentations, most of which are summarised here in writing, and all
participants who have actively contributed to the discussions. Finally,
we also wish to thank
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