Ann Rheum Dis 2000;59:985-994 ( December )

Meeting report

A report from a symposium held at Klinikum Benjamin Franklin, Free University, Berlin, Germany, 25-26 February 2000

Enthesitis and ankylosis in spondyloarthropathy: What is the target of the immune response?

J Braun, M A Khan, J Sieper

Department of Rheumatology, UK B Franklin, Free University, Berlin, Germany

Correspondence to: Professor J Braun, Department of Rheumatology, Medizinische Klinik IV, Universitätsklinikum Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany jbraun@zedat.fu-berlin.de

Accepted for publication 9 August 2000

The first 150 words of the full text of this article appear below.

	Introduction

This symposium was organised by J Braun and J Sieper (Free University, Berlin) to review the current knowledge of the anatomical, inflammatory, microbiological, and immunological events in enthesitis.

The term "enthesopathy" is relatively new and its medical history short, but some important contributions can be listed (box 1).

Figure Removed (Available Only in the Full Text)

The spondyloarthropathies are among the most common inflammatory rheumatic diseases.¹ In addition to the strong genetic predisposition, partly due to HLA-B27,² there are characteristic clinical features of SpA³: inflammatory back pain often due to sacroiliitis⁴ and enthesitis occurring mostly at various well defined locations, predominantly of the legs, such as the Achilles tendon, the plantar aponeurosis, the knee, the trochanter regions of the femur, and several pelvic sites.⁵ Thus entheses are ubiquitous, resulting in a diversity of associated pathological manifestations.

Sacroiliitis is the most common early sign of SpA.⁶ Whether or not ligamentous and entheseal structures are affected in sacroiliac . . . [Full text of this article]

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