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Annals of the Rheumatic Diseases 2000;59:2-4; doi:10.1136/ard.59.1.2
Copyright © 2000 BMJ Publishing Group Ltd & European League Against Rheumatism.
Ann Rheum Dis 2000;59:2-4 ( January )

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Diagnosis and treatment of mood disorders in patients with rheumatic disease

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Mood disorders are common among the medically ill and tend to worsen, as illness becomes more severe. Major depressive disorder (MDD) occurs in 4-6% of the general population, in 5-10% of medically ill outpatients, and in 10-30% of hospitalised medical inpatients.1-3 Rheumatic diseases such as fibromyalgia, chronic fatigue/pain syndromes, rheumatoid arthritis, systemic lupus erythematosus (SLE), scleroderma, and Sjögren's syndrome (SS) are associated with psychiatric disorders or symptom states. Depression is associated with increased functional disability, pain, and stressors like low autonomy, low income, marital status and high demands.4 5 By nature recurrent and progressive, it should be diagnosed and treated as soon as possible.

Patients with fibromyalgia and chronic fatigue/pain syndromes have premorbid and significantly higher rates of psychiatric disorders than do patients with rheumatoid arthritis, who were found to have similar rates of depression when compared with those with other chronic medical illnesses.6 7 In patients with rheumatological disease, SLE is . . . [Full text of this article]


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This article has been cited by other articles:

  • Maiden, N. L., Hurst, N. P., Lochhead, A., Carson, A. J., Sharpe, M. (2003). Quantifying the burden of emotional ill-health amongst patients referred to a specialist rheumatology service. Rheumatology (Oxford) 42: 750-757 [Abstract] [Full Text]  
  • Stoll, T., Kauer, Y., Buchi, S., Klaghofer, R., Sensky, T., Villiger, P. M. (2001). Prediction of depression in systemic lupus erythematosus patients using SF-36 Mental Health scores. Rheumatology (Oxford) 40: 695-698 [Abstract] [Full Text]  

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