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Diagnosis and treatment of mood disorders in patients with rheumatic disease
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Mood disorders are common among the medically ill and tend to worsen, as illness becomes more severe. Major depressive disorder (MDD) occurs in 4-6% of the general population, in 5-10% of medically ill outpatients, and in 10-30% of hospitalised medical inpatients.1-3 Rheumatic diseases such as fibromyalgia, chronic fatigue/pain syndromes, rheumatoid arthritis, systemic lupus erythematosus (SLE), scleroderma, and Sjögren's syndrome (SS) are associated with psychiatric disorders or symptom states. Depression is associated with increased functional disability, pain, and stressors like low autonomy, low income, marital status and high demands.4 5 By nature recurrent and progressive, it should be diagnosed and treated as soon as possible.
Patients with fibromyalgia and chronic fatigue/pain syndromes have
premorbid and significantly higher rates of psychiatric disorders than
do patients with rheumatoid arthritis, who were found to have similar
rates of depression when compared with those with other chronic medical
illnesses.6 7 In patients with rheumatological disease,
SLE is
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(2003). Quantifying the burden of emotional ill-health amongst patients referred to a specialist rheumatology service. Rheumatology (Oxford)
42: 750-757
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Stoll, T., Kauer, Y., Buchi, S., Klaghofer, R., Sensky, T., Villiger, P. M.
(2001). Prediction of depression in systemic lupus erythematosus patients using SF-36 Mental Health scores. Rheumatology (Oxford)
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