Lesson of the month
Non-Hodgkin's lymphoma presenting with spinal involvement
B Vanneuvillea, A Janssensb, M Lemmerlingc, K de Vlama, H Mielantsa, E M Veysa
a Departments
of Rheumatology, b Haematology, c and Radiology, d University
Hospital Ghent, Belgium
Correspondence to: Professor Dr E M Veys, Department of Rheumatology, University Hospital Gent, Pintelaan 185, B-9000 Gent, Belgium.
Accepted for publication 22 July 1999
| The first 150 words of the full text of this article appear below. |
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Case report 1 |
|---|
The case concerns a 38 year old woman with a one year history of a low grade non-Hodgkin's lymphoma stage 4 (disseminated involvement of one or more extralymphatic organs with or without lymph node involvement). At the time of diagnosis, nodal involvement was found in the supraclavicular and axillar regions and in the neck; the abdomen presented marked splenomegaly and sternal puncture revealed bone marrow involvement. Restaging after treatment with cyclofosfamide-vincristine-prednisone (CVP) and cyclofosfamide-epirubicine-vincristine-prednisone (CEOP) chemotherapy during 10 months showed the absence of pathological node with computed tomography (CT).
One year after diagnosis, the patient consulted the department of
haematology with sudden onset of low back pain and sciatica in the
right leg. The complaints resolved after treatment with non-steroidal
anti-inflammatory drugs (NSAIDs). Three weeks later, she presented a
relapse of the sciatica with dysaesthesia and sensory deficit of the
right leg and progressive paresis of the right leg, however no systemic
features
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This article has been cited by other articles:
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Morcos, F, Smith, E
(2002). Sciatica or spinal lymphoma. Ann Rheum Dis
61: 94-94
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