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Will the increasing prevalence of atopy have a favourable impact on rheumatoid arthritis?
See article on page 275| The first 150 words of the full text of this article appear below. |
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Changes in the prevalence or incidence of certain diseases over
time are likely to provide clues to pathogenesis. While we rheumatologists worry from time to time about the possible
disappearance of rheumatoid arthritis (RA), one of our major reasons
for getting up in the morning,1 2 our colleagues in the
chest and allergy clinics have no such anxieties, presiding as they do
over a substantial increase in the prevalence of asthma and other
atopic disorders.3 Particularly striking have been the
changes, over comparatively short periods of time, in the prevalence of
atopic disorders in countries of the former Eastern bloc, particularly
East Germany, where relative genetic homogeneity of the populations in
the former East Germany and West Germany makes comparisons particularly
telling. Thus despite heavy levels of atmospheric pollution in the
east, which would have been thought likely to exacerbate respiratory diseases, the prevalence of asthma was found to be considerably
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Ann Rheum Dis 1998 57: 275-280.[Abstract] [Full Text] [PDF]
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