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Imaging the joint and enthesis: insights into pathogenesis of psoriatic arthritis

D McGonagle

Correspondence to:
Correspondence to:
Prof D McGonagle
Academic Unit Musculoskeletal Diseases, University of Leeds, and Calderdale Royal Hospital, Salterhebble, Halifax HX3 0PW, UK; d.g.mcgonagle{at}leeds.ac.uk

The distinct radiographic features of psoriatic arthritis (PsA) help confirm it as a distinct entity from rheumatoid arthritis and highlight some unique non-synovial based disease imaging features. The advent of magnetic resonance imaging and a better understanding of joint microanatomy including the complexity of joint entheses provide a unifying anatomical and biomechanical concept that links disease at the apparently disparate sites of involvement in PsA, including the synovium, the enthesis, the bone and the periosteum. These findings suggest a reason for the localisation of disease to skeletal sites that are subject to repeated mechanical stressing.

Abbreviations: MRI, magnetic resonance imaging; PsA, psoriatic arthritis; RA, rheumatoid arthritis; SpA, spondyloarthropathy

Keywords: enthesis; magnetic resonance imaging; pathogenesis; psoriasis; psoriatic arthritis

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