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Published Online First: 11 November 2004. doi:10.1136/ard.2004.027086
Annals of the Rheumatic Diseases 2005;64:936-939
Copyright © 2005 BMJ Publishing Group Ltd & European League Against Rheumatism.
Annals of the Rheumatic Diseases 2005;64:936-939
© 2005 by BMJ Publishing Group Ltd & European League Against Rheumatism

EXTENDED REPORT

Lumbosacral radiographic signs in patients with previous enteroarthritis or uroarthritis

A Mannoja1, J Pekkola1, M Hämäläinen1, M Leirisalo-Repo2, L Laasonen1, L Kivisaari1

1 Department of Radiology, Helsinki University Central Hospital, Helsinki, Finland
2 Department of Medicine, Division of Rheumatology, Helsinki University Central Hospital

Correspondence to:
Dr Antti Mannoja
Marjatie 6b, FIN-00780, Helsinki, Finland; antti.mannoja{at}helsinki.fi

Objective: To investigate if there are differences in radiological findings in lumbosacral spine radiographs between different subgroups of patients with previous reactive arthritis.

Methods: 95 patients with previous enteroarthritis (n = 53), uroarthritis (n = 37), or Reiter’s syndrome, aetiology unknown (n = 5) were included in the study. Lumbosacral radiographs were taken 7 to 38 years after the initial arthritis. Three independent observers read the radiographs. Spinal changes included squaring of vertebrae, Romanus lesions, syndesmophytes, and osteophytes. Sacroiliitis was recorded according to the New York and Stoke methods. Signs of enthesitis in the iliac crest and disc space narrowing were recorded. Interobserver reliability and intraobserver reproducibility were determined.

Results: 23% of patients had grade 2–4 sacroiliitis (New York criteria) and 14% had syndesmophytes. There was more frequent sacroiliitis (32% v 13%) in uroarthritis than in enteroarthritis, and more syndesmophytes (mean 0.54 v 0.15 per patient; prevalence 24% v 6%, respectively). In other radiological features, no significant differences were present between the groups. In the material as a whole, patients with sacroiliitis of grade 2 or more had significantly less disc space narrowing both in patient comparisons ({chi}2 test) and in numbers of spaces involved (Mann-Whitney test). Interobserver and intraobserver agreement, calculated using Cohen’s {kappa} method, varied from 0.2 to 1.

Conclusions: Syndesmophytes and sacroiliitis are more common in patients with previous uroarthritis than in those with previous enteroarthritis, but radiological findings in lumbosacral spine radiographs are characteristically similar.

Keywords: reactive arthritis; sacroiliac joint; spondyloarthropathies


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