REVIEW

Intra-articular treatments in osteoarthritis: from the symptomatic to the structure modifying

L Gossec, M Dougados

René Descartes University, Cochin Hospital, Rheumatology B Department, Paris, France

Correspondence to:
Correspondence to:
Dr L Gossec
27 rue du Fbg, St Jacques, Paris 75014, France; laure.gossec{at}cch.ap-hop-paris.fr

The symptomatic and structural efficacy of intra-articular (IA) injections is reviewed. IA corticosteroid injections are rapidly effective, but their symptomatic benefit is short lived. Hyaluronan has delayed onset of efficacy but its benefit for pain may be longer lasting. Lavage and debridement are probably not as efficacious as once thought in osteoarthritis.

Keywords: hyaluronan; intra-articular treatments; corticosteroids; lavage; osteoarthritis

Abbreviations: HA, hyaluronic acid; IA, intra-articular; NSAIDs, non-steroidal anti-inflammatory drugs; OA, osteoarthritis; RCT, randomised controlled trial; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index

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