Register for email alerts and news feeds:
This journal | BMJ Group
rss
Annals of the Rheumatic Diseases 2002;61:718-722; doi:10.1136/ard.61.8.718
Copyright © 2002 BMJ Publishing Group Ltd & European League Against Rheumatism.
Annals of the Rheumatic Diseases 2002;61:718-722
© 2002 by Annals of the Rheumatic Diseases

EXTENDED REPORT

Standardised nomenclature for glucocorticoid dosages and glucocorticoid treatment regimens: current questions and tentative answers in rheumatology

F Buttgereit1, J A P Da Silva2, M Boers3, G-R Burmester1, M Cutolo4, J Jacobs5, J Kirwan6, L Köhler7, P van Riel8, T Vischer9, J W J Bijlsma5

1 Department of Rheumatology and Clinical Immunology, Charité University Hospital, Humboldt University, Berlin, Germany
2 Department of Rheumatology, Coimbra University, Portugal
3 Department of Clinical Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam, The Netherlands
4 Division of Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy
5 Department of Rheumatology and Clinical Immunology, University Medical Centre, Utrecht, The Netherlands
6 Rheumatology Unit, Division of Medicine, University of Bristol, Bristol, United Kingdom
7 Division of Rheumatology, Medizinische Hochschule Hannover, Hannover, Germany
8 Department of Rheumatology, University Medical Centre, Nijmegen, The Netherlands
9 Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland

Correspondence to:
Correspondence to:
Dr F Buttgereit, Department of Rheumatology and Clinical Immunology, Charité University Hospital, Schumannstrasse 20/21, 10117 Berlin, Germany;
frank.buttgereit{at}charite.de

In rheumatology and other medical specialties there is a discrepancy between the widespread use and the imprecise designation of glucocorticoid treatment regimens. Verbal descriptions of glucocorticoid treatment regimens used in various phases of diseases vary between countries and institutions. Given this background, a workshop under the auspices of the EULAR Standing Committee on International Clinical Studies including Therapeutic Trials was held to discuss this issue and to seek a consensus on nomenclature for glucocorticoid treatment. This report summarises the panel's discussion and recognises that answers derived from consensus conferences are not definitive. Nevertheless, recommendations on glucocorticoid treatment are presented that (1) reflect current and best knowledge available and (2) take into account current clinical practice. A question-answer rationale presentation style has been chosen to convey the messages, to summarise the meeting in a readable format, and to avoid dogmatism.

Keywords: nomenclature; glucocorticoid treatments


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?

This article has been cited by other articles:

  • Naumann, L, Huscher, D, Detert, J, Spengler, M, Burmester, G-R, Buttgereit, F (2009). Anti-tumour necrosis factor {alpha} therapy in patients with rheumatoid arthritis results in a significant and long-lasting decrease of concomitant glucocorticoid treatment. Ann Rheum Dis 68: 1934-1936 [Full Text]  
  • Hoes, J N, Jacobs, J W G, Verstappen, S M M, Bijlsma, J W J, Van der Heijden, G J M G (2009). Adverse events of low- to medium-dose oral glucocorticoids in inflammatory diseases: a meta-analysis. Ann Rheum Dis 68: 1833-1838 [Abstract] [Full Text]  
  • Grijalva, C. G., Kaltenbach, L., Arbogast, P. G., Mitchel, E. F. Jr, Griffin, M. R. (2009). Initiation of rheumatoid arthritis treatments and the risk of serious infections. Rheumatology (Oxford) 0: kep325v1-kep325 [Abstract] [Full Text]  
  • Huscher, D, Thiele, K, Gromnica-Ihle, E, Hein, G, Demary, W, Dreher, R, Zink, A, Buttgereit, F (2009). Dose-related patterns of glucocorticoid-induced side effects. Ann Rheum Dis 68: 1119-1124 [Abstract] [Full Text]  
  • Ravindran, V., Rachapalli, S., Choy, E. H. (2009). Safety of medium- to long-term glucocorticoid therapy in rheumatoid arthritis: a meta-analysis. Rheumatology (Oxford) 48: 807-811 [Abstract] [Full Text]  
  • Panoulas, V. F., Douglas, K. M. J., Smith, J. P., Stavropoulos-Kalinoglou, A., Metsios, G. S., Nightingale, P., Kitas, G. D. (2009). Transforming growth factor-{beta}1 869T/C, but not interleukin-6 -174G/C, polymorphism associates with hypertension in rheumatoid arthritis. Rheumatology (Oxford) 48: 113-118 [Abstract] [Full Text]  
  • Panoulas, V. F., Metsios, G. S., Pace, A. V., John, H., Treharne, G. J., Banks, M. J., Kitas, G. D. (2008). Hypertension in rheumatoid arthritis. Rheumatology (Oxford) 47: 1286-1298 [Abstract] [Full Text]  
  • Cutolo, M., Straub, R. H, Buttgereit, F. (2008). Circadian rhythms of nocturnal hormones in rheumatoid arthritis: translation from bench to bedside. Ann Rheum Dis 67: 905-908 [Full Text]  
  • Panoulas, V. F., Douglas, K. M. J., Stavropoulos-Kalinoglou, A., Metsios, G. S., Nightingale, P., Kita, M. D., Elisaf, M. S., Kitas, G. D. (2008). Long-term exposure to medium-dose glucocorticoid therapy associates with hypertension in patients with rheumatoid arthritis. Rheumatology (Oxford) 47: 72-75 [Abstract] [Full Text]  
  • Panoulas, V. F., Douglas, K. M. J., Milionis, H. J., Stavropoulos-Kalinglou, A., Nightingale, P., Kita, M. D., Tselios, A. L., Metsios, G. S., Elisaf, M. S., Kitas, G. D. (2007). Prevalence and associations of hypertension and its control in patients with rheumatoid arthritis. Rheumatology (Oxford) 46: 1477-1482 [Abstract] [Full Text]  
  • Parker, B., Bruce, I. (2007). High dose methylprednisolone therapy for the treatment of severe systemic lupus erythematosus. Lupus 16: 387-393 [Abstract]  
  • Spies, C M, Schaumann, D H S, Berki, T, Mayer, K, Jakstadt, M, Huscher, D, Wunder, C, Burmester, G-R, Radbruch, A, Lauster, R, Scheffold, A, Buttgereit, F (2006). Membrane glucocorticoid receptors are down regulated by glucocorticoids in patients with systemic lupus erythematosus and use a caveolin-1-independent expression pathway. Ann Rheum Dis 65: 1139-1146 [Abstract] [Full Text]  
  • Da Silva, J A P, Jacobs, J W G, Kirwan, J R, Boers, M, Saag, K G, Ines, L B S, de Koning, E J P, Buttgereit, F, Cutolo, M, Capell, H, Rau, R, Bijlsma, J W J (2006). Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data. Ann Rheum Dis 65: 285-293 [Abstract] [Full Text]  
  • Buttgereit, F, Burmester, G, Bijlsma, J W, Durez, P, Nzeusseu Toukap, A, Lauwerys, B R, Manicourt, D H, Devogelaer, J-P, Houssiau, F A, Verschueren, P, Westhovens, R (2005). Which dose regimen for glucocorticoid pulse therapy in patients with severe refractory RA? * Authors' reply. Ann Rheum Dis 64: 171-172 [Full Text]  
  • Durez, P, Nzeusseu Toukap, A, Lauwerys, B R, Manicourt, D H, Verschueren, P, Westhovens, R, Devogelaer, J-P, Houssiau, F A (2004). A randomised comparative study of the short term clinical and biological effects of intravenous pulse methylprednisolone and infliximab in patients with active rheumatoid arthritis despite methotrexate treatment. Ann Rheum Dis 63: 1069-1074 [Abstract] [Full Text]  
  • Bijlsma, J W J, Boers, M, Saag, K G, Furst, D E (2003). Glucocorticoids in the treatment of early and late RA. Ann Rheum Dis 62: 1033-1037 [Full Text]  
  • Cutolo, M, Seriolo, B, Craviotto, C, Pizzorni, C, Sulli, A (2003). Circadian rhythms in RA. Ann Rheum Dis 62: 593-596 [Full Text]  
  • Kirwan, J (2003). Principles of glucocorticoid therapy: Eds A N Lin, S A Paget. (85.) London: Arnold, 2002. ISBN 0 340 75934-8.. Ann Rheum Dis 62: 495-496 [Full Text]  

This Article

Services
Citing Articles
Google Scholar
PubMed
Bookmark with

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

BMJ Careers - Latest Rheumatology Jobs

Rheumatology Jobs