© 2002 by Annals of the Rheumatic Diseases
CONCISE REPORT
Rheumatological complications associated with the use of indinavir and other protease inhibitors
1 Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
Correspondence to:
Correspondence to:
Professor Colebunders, Department of Clinical Research, Institute of Tropical Medicine, Nationalestraat, 155, B-1000 Antwerp, Belgium;
bcoleb{at}itg.be
Several cases are reported of rheumatological pathology (temporomandibular dysfunction, frozen shoulder, Dupuytren's disease, and tendinitis) most probably related to the intake of indinavir in HIV positive patients. A survey using an anonymous questionnaire of 878 people with HIV infection treated with antiretroviral drugs suggests that other protease inhibitors may also cause arthralgia.
Keywords: arthritis; frozen shoulder; HIV infection; protease inhibitor indinavir
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