Extended report
A case-control study to investigate the relation between low and
moderate levels of physical activity and osteoarthritis of the knee
using data collected as part of the Allied Dunbar National Fitness
Survey
A J Suttona, K R Muirb, S Mockettc, P Fentemd
a Department of
Epidemiology and Public Health, University of Leicester, 22-28
Princess Road West, Leicester LE1 6TP, UK, b Division of Public Health Medicine and
Epidemiology, University of Nottingham, University Hospital Queen's
Medical Centre, Nottingham NG7 2UH, UK, c Division of Physiotherapy Education, School of
Community Health Science, Faculty of Medicine and Health Sciences,
University of Nottingham, UK, d Division
of Stroke Medicine, University of Nottingham, Nottingham City Hospital
(NHS) Trust, UK
Correspondence to: Mr Sutton ajs22{at}le.ac.uk
Accepted for publication 12 January
2001
BACKGROUND
Physical
activity is being recommended as an intervention for seemingly almost
universal improvements to health. A potential concern with this
recommendation for increased exercise is that some believe increased
levels of activity may lead to increased incidence of osteoarthritis of
the knee (knee OA), as a result of accelerated "wear and tear" of
the major joints.
OBJECTIVE
To
investigate the hypothesis that the occurrence of knee OA may be
related to the duration of participation in some forms of sport and
active recreation.
METHODS
The relation
between habitual exercise, reported by a cross section of people
surveyed in England, and self reported knee OA was investigated. Data
were derived from the Allied Dunbar National Fitness Survey (1990-91).
A matched retrospective case-control design was used and a new exposure
classification system which categorised different grades of activities
for different time periods for each subject's lifetime participation
in regular physical activities was developed. Additional data on knee
injuries sustained and bodily composition were also included in a
multivariate analysis.
RESULTS
From 4316 people originally interviewed, 216 eligible cases (66 men, 150 women)
were identified (mean age 57.1). Each case was matched to four
controls. When habitual sport/exercise participation were examined
during a subject's life, only exposure to regular long walks and being
physically active between the ages of 20 and 24 suggested any
association with developing knee OA later in life. The only strong
association found was a greatly increased risk of knee OA having
previously sustained a knee injury (p<0.01, odds ratio 8.0 (95%
confidence interval 2.0 to 32.0)).
CONCLUSIONS
There was
little evidence to suggest that increased levels of regular physical
activity throughout life lead to an increased risk of knee OA later in
life. Previous knee injury was associated with an increased risk of
knee OA. Additionally, most injuries were caused through participation
in physical activities. Hence, when deciding on participation in
activities, it is worth taking the likelihood of joint injury into
consideration, as the chance of injury is greater in some activities
than others.
© 2001 by Annals of the Rheumatic Diseases
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