Extended report
Regional differences in the incidence of rheumatoid arthritis in
Finland in 1995
O Kaipiainen-Seppänena, K Ahob, M Nikkarinenc
a Department of
Medicine, Kuopio University Hospital, Kuopio, Finland, b National Public Health
Institute, Helsinki, Finland, c Geological Survey of Finland, Kuopio, Finland
Correspondence to: Dr O Kaipiainen-Seppänen, Department of Medicine, PO Box 1777, Kuopio University Hospital, 70211 Kuopio, Finland Oili.Kaipiainen-Seppanen{at}kuh.fi
Accepted for publication 13 June 2000
OBJECTIVE
To
investigate regional differences in the incidence of rheumatoid
arthritis (RA).
METHODSThose subjects
entitled to receive drug reimbursement for chronic inflammatory joint
diseases in 11/21 central hospital districts (population base about 1.8 million adults) in Finland during 1995 were studied. The incidence
rates from these central hospital districts were compared.
RESULTSA total of
1213 subjects were entitled to drug reimbursement for chronic
inflammatory joint disease which had started at the age of 16 or over.
Of these, 598 subjects satisfied the American Rheumatism Association
1987 criteria for RA. The age adjusted incidence of RA was
31.7/100 000 (95% CI 29.2 to 34.4) and varied significantly
(p<0.001) among the central hospital districts, ranging from 16.3 to
44.8/100 000.
CONCLUSIONThere are
regional differences in the incidence of RA. The reasons for these are
probably environmental rather than genetic.
© 2001 by Annals of the Rheumatic Diseases
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