Review
Two forms of reactive arthritis?
Paavo Toivanen, Auli Toivanen
Turku Immunology
Centre, Departments of Medical Microbiology and Medicine, Turku
University, Turku, Finland
Correspondence to: Dr P Toivanen, Department of Medical Microbiology, Turku University, FIN-20520 Turku, Finland
Accepted for publication 26 August 1999
Inflammatory arthritides developing after a distant infection
have so far been called reactive or postinfectious, quite often depending on the microbial trigger and/or HLA-B27 status of the patient. For clarity, it is proposed that they all should be called reactive arthritis, which, according to the trigger, occurs as an
HLA-B27 associated or non-associated form. In addition to the causative
agents and HLA-B27, these two categories are also distinguished by
other characteristics. Most important, HLA-B27 associated arthritis may
occur identical to the Reiter's syndrome with accompanying uretheritis
and/or conjunctivitis, whereas in the B27 non-associated form this has
not been clearly described. Likewise, only the B27 associated form
belongs to the group of spondyloarthropathies.
© 1999 by Annals of the Rheumatic Diseases
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This article has been cited by other articles:
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Sibilia, J, Limbach, F-X
(2002). Reactive arthritis or chronic infectious arthritis?. Ann Rheum Dis
61: 580-587
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