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Annals of the Rheumatic Diseases 1998;57:107-109; doi:10.1136/ard.57.2.107
Copyright © 1998 BMJ Publishing Group Ltd & European League Against Rheumatism.
Ann Rheum Dis 1998;57:107-109 ( February )

Concise reports

Quality control of synovial fluid crystal identification Robert von Essen,a Aira M H Hölttä,a Raija Pikkarainenb

a Rheumatism Foundation Hospital, Heinola, Finland, b Labquality, Helsinki, Finland

Correspondence to: Dr R Pikkarainen, Labquality, Ratamestarinkatu 11, FIN-00520 Helsinki, Finland.

Accepted for publication 13 November 1997

OBJECTIVE---To establish a quality assessment programme for the diagnosis of crystal arthropathies by synovial fluid (SF) microscopy.
METHODS---Three or four cytocentrifuge slides prepared from suitable patient SF specimens were distributed to 25-47 predominantly Finnish clinical laboratories once a year. Sodium urate crystals were included in every survey.
RESULTS---Returns for the years 1989-1996 were reviewed. Laboratories that participated in > four surveys made on an average one error a year (range 0.25-2). The error rate for specimens containing abundant crystals was acceptable but it increased considerably for specimens showing few crystals per microscope field. No laboratory characteristic predictive of successful performance was found.
CONCLUSION---Errors in quality assessment results for crystal identification were much more frequent than in the fields of, for example, clinical chemistry or microbiology. Despite efforts to provide educational feedback, no improvement was seen during the study period. Because of the dearth of data from other parts of the world it is not known for certain whether this study has merely pinpointed a local problem or if the same trend applies elsewhere.

Keywords: synovial fluid; joint fluid; quality control; crystals


© 1998 by Annals of the Rheumatic Diseases

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  • Lumbreras, B, Pascual, E, Frasquet, J, Gonzalez-Salinas, J, Rodriguez, E, Hernandez-Aguado, I (2005). Analysis for crystals in synovial fluid: training of the analysts results in high consistency. Ann Rheum Dis 64: 612-615 [Abstract] [Full Text]  
  • Galvez, J, Saiz, E, Linares, L F, Climent, A, Marras, C, Pina, M F, Castellon, P (2002). Delayed examination of synovial fluid by ordinary and polarised light microscopy to detect and identify crystals. Ann Rheum Dis 61: 444-447 [Abstract] [Full Text]  

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