Antiperinuclear factors are present in polyarthritis before ACR criteria for rheumatoid arthritis are fulfilled

doi:10.1136/ard.56.2.123

Annals of the Rheumatic Diseases 1997;56:123-125; doi:10.1136/ard.56.2.123

Ann Rheum Dis 1997;56:123-125 ( February )

Concise reports

Antiperinuclear factors are present in polyarthritis before ACR criteria for rheumatoid arthritis are fulfilled Jean-Marie Berthelot,^a Yves Maugars,^a Anne Castagné,^a Marie Audrain,^b Alain Prost^a

^a Hôtel-Dieu, CHU Nantes, BP 1005, 44035 Nantes Cedex 01, France: Service de Rhumatologie, ^b Laboratoire d'Immunologie

Correspondence to: and reprint requests to: Dr J-M Berthelot, Service de Rhumatologie, Hôtel-Dieu, CHU Nantes, BP 1005, 44035 Nantes Cedex 01, France.

Accepted for publication 18 November 1996

OBJECTIVE $---$ To show that antiperinuclear factor (APF) may be useful for the diagnosis of rheumatoid arthritis at a time when the AmericanCollege of Rheumatology (ACR) criteria are not yetfulfilled.
METHODS $---$ Testing for APF-IgG (1:100 threshold) and rheumatoid factors (RF) was done in 60 patients with polyarthritis of recent onsetduring a three year followup.
RESULTS $---$ At the end of the study, 21/40 rheumatoid arthritis were positive for RF and 31/40 for APF, including 18/40 cases (45%) inwhich ACR criteria were not yetfulfilled.
CONCLUSIONS $---$ APF are useful in the diagnosis of early rheumatoidarthritis.

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati What's this?

This article has been cited by other articles:

Chapuy-Regaud, S., Sebbag, M., Baeten, D., Clavel, C., Foulquier, C., De Keyser, F., Serre, G. (2005). Fibrin Deimination in Synovial Tissue Is Not Specific for Rheumatoid Arthritis but Commonly Occurs during Synovitides. J. Immunol. 174: 5057-5064 [Abstract] [Full Text]
Caponi, L, Petit-Teixeira, E, Sebbag, M, Bongiorni, F, Moscato, S, Pratesi, F, Pierlot, C, Osorio, J, Chapuy-Regaud, S, Guerrin, M, Cornelis, F, Serre, G, Migliorini, P, for ECRAF, (2005). A family based study shows no association between rheumatoid arthritis and the PADI4 gene in a white French population. Ann Rheum Dis 64: 587-593 [Abstract] [Full Text]
Vencovsky, J, Machacek, S, Sedova, L, Kafkova, J, Gatterova, J, Pesakova, V, Ruzickova, S (2003). Autoantibodies can be prognostic markers of an erosive disease in early rheumatoid arthritis. Ann Rheum Dis 62: 427-430 [Abstract] [Full Text]
Meyer, O, Labarre, C, Dougados, M, Goupille, P., Cantagrel, A, Dubois, A, Nicaise-Roland, P, Sibilia, J, Combe, B (2003). Anticitrullinated protein/peptide antibody assays in early rheumatoid arthritis for predicting five year radiographic damage. Ann Rheum Dis 62: 120-126 [Abstract] [Full Text]
Masson-Bessiere, C., Sebbag, M., Girbal-Neuhauser, E., Nogueira, L., Vincent, C., Senshu, T., Serre, G. (2001). The Major Synovial Targets of the Rheumatoid Arthritis-Specific Antifilaggrin Autoantibodies Are Deiminated Forms of the {{alpha}}- and {{beta}}-Chains of Fibrin. J. Immunol. 166: 4177-4184 [Abstract] [Full Text]
Paimela, L, Palosuo, T, Aho, K, Lukka, M, Kurki, P, Leirisalo-Repo, M, von Essen, R (2001). Association of autoantibodies to filaggrin with an active disease in early rheumatoid arthritis. Ann Rheum Dis 60: 32-35 [Abstract] [Full Text]
BOERBOOMS;, A. M T H, BERTHELOT, J-M (1997). Antiperinuclear factors are present in polyarthritis before ACR criteria for rheumatoid arthritis are fulfilled. Ann Rheum Dis 56: 395a-396 [Full Text]

Services

Citing Articles

Google Scholar

PubMed

Topic Collections

Bookmark with

What's this?

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.